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Fixed snapshotThis page is a fixed snapshot of 2026-08-19 (UTC). It is never updated. The ranking that updates daily lives on the latest edition.

Past 24 hours

24-Hour Movers (2026-08-19)

A full-market scan narrowed to the ten biggest moves. Every attribution carries its evidence tier on the badge — first-party filing, press coverage, or an honest blank. Numbers only ever come from first-party sources.

Data updated
2026-08-19 19:36
Instruments scanned
312
Past 24 hours
24 h

All times in UTC

Change

MRNA+164.97%TEM+22.84%TWST+20.69%BNTX+20.41%HYPE-USDT+19.49%EL+17.94%DOS-USDT+16.25%HYMC+15.01%IOVA+14.44%DRD+14.40%
Rank1

Moderna, Inc.

MRNA

+164.97%
US equitiesUnited States
Last 24 hourly closes · 1H
MRNA
Last price166.83 USD
Change+164.97%
Intraday range45.84%
Volume vs baseline166.1×
Sigma move38.4 σ
Rank in past 100 days#1
Move started2026-08-19 13:30opening bell
Part of this storySecondary (media)Confidence · Medium

The first mRNA treatment meant to prevent cancer came back with positive Phase 3 results: Moderna +165% in a single session, and 4 tickers riding the same personalized-medicine route were repriced with it. Top comment on r/stocks, 608 upvotes: “Now it's only down 84% on the 5yr.”

MechanismWhat read out is not one drug but a route: sequence the patient's own tumor, pick the mutations worth hitting, manufacture an mRNA vaccine for that single person, then give it after surgery alongside Keytruda to hold recurrence and spread down. The Phase 3 met its primary endpoint — the first time an mRNA cancer vaccine has held up in a late-stage trial. Enrolment size and the formal endpoint names are figures we could not source that day: neither Moderna nor Merck had filed anything with the SEC in the previous four days, so this paragraph stays qualitative and prints no clinical numbers at all — if you cannot click through to a figure from this card, we do not print it. That is also why the repricing did not stop at Moderna: BioNTech runs the rival individualized-mRNA program, Tempus sequences tumors, Iovance sells a personalized cell therapy for melanoma — the market bought the route, not the ticker. The news landed premarket and 3 of the 4 names gapped straight at the bell, so the lag for this cluster cannot be measured and we do not print one.

Event time
2026-08-19 · premarket
Lag
priced at the bell — not measurable

Top post at the time

What people said

Quoted verbatim, wording unchanged; the other languages are translations. Vote counts are a snapshot from the moment we fetched them.

Now it's only down 84% on the 5yr.
u/luv2block608reddit
wow this huge!! taking a piece of a patient's tumor, mapping its genes and printing a custom mRNA shot to train the body to hunt down remaining cancer cells sounds like sci-fi, but it actually worked…
u/PortfolioTrackr512reddit

Tickers in this thread

0%+50%+100%+150%MRNA+164.97%TEM+22.84%BNTX+20.41%IOVA+14.44%
24-hour moves for every ticker in this story, drawn on one shared axis. Every bar is a measurement we took.
#2 TEM#4 BNTX#9 IOVA

Press coverage only — no first-party filing came back. Confidence is therefore capped at medium: we know what happened, just not from the party it happened to.

Sources

Measured from
Catalyst source
Leads
Secondary (media)Stocktwits2026-08-19 17:49Secondary (media)24/7 Wall St.2026-08-19 18:44Secondary (media)r/stocks2026-08-19 11:12
Rank2

Tempus AI, Inc.

TEM

+22.84%
US equitiesUnited States
Last 24 hourly closes · 1H
TEM
Last price60.63 USD
Change+22.84%
Intraday range12.02%
Volume vs baseline9.2×
Sigma move4.9 σ
Rank in past 100 days#1
Move started2026-08-19 15:30

Same thread as #1 MRNA — The first mRNA treatment meant to prevent cancer came back with positiv…

The catalyst, the mechanism, the posts and the sources all sit in that block. Nothing is repeated here.

Sources

Only the sources unique to this row. Anything already listed in that block is not repeated here.

Measured from
Rank3

Twist Bioscience Corporation

TWST

+20.69%
US equitiesUnited States
Last 24 hourly closes · 1H
TWST
Last price140.12 USD
Change+20.69%
Intraday range10.70%
Volume vs baseline9.7×
Sigma move3.7 σ
Rank in past 100 days#1
Move started2026-08-19 13:30opening bell
Part of this storyFirst-partyConfidence · Medium

Twist +21% in a session — and not on the mRNA vaccine readout next door. Its own 8-K says it plainly: Anthropic picked Twist as one of the independent evaluators for its AI-designed proteins.

MechanismThe easy mistake on a day like this is to fold it into the vaccine cluster: a handful of tickers up hard in the same direction really does look like one trade. But not one piece of Twist's own evidence mentions a vaccine. Its 8-K from 22:15 UTC the previous evening (Item 7.01, Regulation FD) reports that Anthropic got data back on a multi-arm protein design campaign against 15 targets and chose Twist as one of its independent evaluators; the MT Newswires confirmation later that session says the same thing; even the dissenting Stocktwits piece is arguing about Anthropic's drug-discovery claims. The buyer base for synthetic DNA widening from vaccine makers to model labs is its own reason to reprice, and it should not borrow anyone else's badge. It gapped at the open too (13:30 UTC), so the lag is again not measurable.

Event time
2026-08-18 · premarket
Lag
priced at the bell — not measurable

Top post at the time

@Cointelegraph29924

🚨 TODAY: Anthropic says Claude successfully designed novel protein binders from scratch for 14 of 15 targets, with Adaptyv Bio and Twist Bioscience independently validating the results.

What people said

Quoted verbatim, wording unchanged; the other languages are translations. Vote counts are a snapshot from the moment we fetched them.

$TWST Twist Biosciences AI drug-discovery story is a speculative delusion with no disclosure of an Anthropic partnership... Anthropic's post stated that 22%-35% of Claude-designed proteins successfully bound their targets...
@ScorpionFund54x
$TWST ... The Chubby Checker stock... (Anthropic has chosen Twist Bioscience Corporation as one of its independent evaluators)...
@MartyChargin21x

This attribution rests on a first-party source — the issuer's own filing or announcement — and the timestamps line up.

Sources

Measured from
Catalyst source
Leads
Secondary (media)Stocktwits2026-08-19 05:21Secondary (media)MT Newswires2026-08-19 18:46Secondary (media)MT Newswires2026-08-19 19:35
Rank4

BioNTech SE

BNTX

+20.41%
US equitiesUnited States
Last 24 hourly closes · 1H
BNTX
Last price111.68 USD
Change+20.41%
Intraday range8.23%
Volume vs baseline62.3×
Sigma move15.5 σ
Rank in past 100 days#1
Move started2026-08-19 13:30opening bell

Same thread as #1 MRNA — The first mRNA treatment meant to prevent cancer came back with positiv…

The catalyst, the mechanism, the posts and the sources all sit in that block. Nothing is repeated here.

Sources

Only the sources unique to this row. Anything already listed in that block is not repeated here.

Measured from
Leads
Secondary (media)MT Newswires2026-08-19 15:18
Rank5

Hyperliquid

HYPE-USDT

+19.49%
CryptoGlobal
Last 24 hourly closes · 1H
HYPE-USDT
Last price70.28 USD
Change+19.49%
Intraday range24.49%
Volume vs baseline18.1×
Sigma move7.4 σ
Rank in past 100 days#1
Move started2026-08-19 15:00
CatalystUnattributedConfidence · Low

Up 19.5% over 24 hours on 18.1× baseline volume — no first-party event in the window lines up on both timing and scope.

Nothing in the window before the move began lines up on both timing and scope — not a first-party filing, not a press report. We would rather leave this blank than supply a reason that merely sounds plausible.

Sources

Measured from
Rank6

The Estée Lauder Companies Inc.

EL

+17.94%
US equitiesUnited States
Last 24 hourly closes · 1H
EL
Last price99.39 USD
Change+17.94%
Intraday range6.22%
Volume vs baseline18.5×
Sigma move10.7 σ
Rank in past 100 days#1
Move started2026-08-19 13:30opening bell
Part of this storyFirst-partyConfidence · Medium

Estée Lauder printed +18% in one session after earnings — and this time the first-party document was in our hands the same day: before the 13:30 UTC bell the company filed its full-year and fourth-quarter fiscal 2026 results, plus fiscal 2027 guidance, with the SEC itself.

MechanismWhat makes this row worth its own paragraph is not the move, it is that the evidence chain actually closed. First-party sources for a single stock are usually out of reach on the day: an 8-K has a four-business-day grace period, and none of the biotech names on this list had filed anything. But earnings-type 8-Ks are nearly always filed before the bell, and this one was: Estée Lauder's Item 2.02 (results of operations) reached EDGAR ahead of the open, saying the company issued its full-year and fourth-quarter fiscal 2026 results that day along with fiscal 2027 net-sales and per-share guidance. So this catalyst is graded primary and does not have to fall back on press coverage. The cost comes with it: the news was premarket, the move starts exactly on the opening bell (13:30 UTC), the lag cannot be measured and we will not invent one. The sell-side's next-day reaction is not part of this write-up — every one of those notes was published after this snapshot was taken, and citing evidence from after our own timestamp is something we do not do.

Event time
2026-08-19 · premarket
Lag
priced at the bell — not measurable

Top post at the time

@CandlePilot5

BREAKING 🚨 Estée Lauder $EL is up ~13% after a strong Q4 earnings beat. Revenue hit $3.63B, up 6.3% YoY, while adjusted EPS came in at $0.39 vs. $0.32 expected.

What people said

Quoted verbatim, wording unchanged; the other languages are translations. Vote counts are a snapshot from the moment we fetched them.

🚨 $EL (Estée Lauder) Fiscal 2026 Earnings Return to growth… but margin recovery + Beauty Reimagined execution are the real story 👀
@EmmanuelInvest4x

This attribution rests on a first-party source — the issuer's own filing or announcement — and the timestamps line up.

Sources

Measured from
Catalyst source
Leads
First-partySEC EDGAR2026-08-19 16:29
Rank7

DOS

DOS-USDT

+16.25%
CryptoGlobal
Last 24 hourly closes · 1H
DOS-USDT
Last price0.2664 USD
Change+16.25%
Intraday range22.78%
Volume vs baseline5.2×
Sigma moven/a
Rank in past 100 daysn/a
Move started2026-08-19 01:00
CatalystUnattributedConfidence · Low

Up 16.3% over 24 hours on 5.2× baseline volume — no first-party event in the window lines up on both timing and scope.

Nothing in the window before the move began lines up on both timing and scope — not a first-party filing, not a press report. We would rather leave this blank than supply a reason that merely sounds plausible.

Sources

Measured from
Rank8

Hycroft Mining Holding Corporation

HYMC

+15.01%
US equitiesUnited States
Last 24 hourly closes · 1H
HYMC
Last price27.82 USD
Change+15.01%
Intraday range6.98%
Volume vs baseline4.9×
Sigma move2.7 σ
Rank in past 100 days#2
Move started2026-08-19 13:30opening bell
Part of this storySecondary (media)Confidence · Medium

Hycroft +15%, DRDGOLD +14%, both gapping on the same opening bell — but what puts them in one story is not a shared headline. It is the industry classification the SEC gives them both — gold and silver ores. Each has news of its own.

MechanismReading this as “gold went up, so gold miners went up” is the natural move, but we hold no gold-price series that would support that sentence, so we do not write it. What we can say: the only thing the two names share is the SEC industry classification for gold and silver ores, and moves of the same order of magnitude — that is all the clustering rests on. The news is separate. Hycroft filed its own 8-K the previous evening (Item 7.01, Regulation FD) reporting a press release with additional drill results from its 2025-2026 exploration drill program; DRDGOLD's side is an MT Newswires write-up of its fiscal 2026 results, published before the bell. Each explains one half of the pair, and the number of candidate articles that would explain both is 0. So the story-level badge takes the weaker of the two legs rather than letting Hycroft's filing vouch for DRDGOLD. Both gapped at the opening bell, so the lag here is not measurable either.

Event time
2026-08-18 · premarket
Lag
priced at the bell — not measurable

Top post at the time

@AMCDiamondHands1452

This is the kind of drill result you love to see. 🔥🥈 $HYMC 145.27 g/t silver over 82.7 meters and Hycroft sitting alone at the top of the silver intercepts. Big width. Strong grade. Real scale.

What people said

Quoted verbatim, wording unchanged; the other languages are translations. Vote counts are a snapshot from the moment we fetched them.

$HYMC ... Hycroft Mining +12% nicely higher after announcing additional drill results... The Brimstone intercept of 82.7 meters at 87.52 g/t silver and 0.77 g/t gold was particularly encouraging...
@MartyChargin13x
Is someone about to get Margin Called and position closed on #HYMC? @HycroftMining is severely lagging the moves in gold and silver… Very suspect…
@Sojka4President186x

Tickers in this thread

0%+5%+10%+15%HYMC+15.01%DRD+14.40%
24-hour moves for every ticker in this story, drawn on one shared axis. Every bar is a measurement we took.
#10 DRD

Press coverage only — no first-party filing came back. Confidence is therefore capped at medium: we know what happened, just not from the party it happened to.

Sources

Measured from
Catalyst source
Leads
Secondary (media)PR Newswire2026-08-18 20:15Secondary (media)MT Newswires2026-08-19 18:56Secondary (media)MarketBeat2026-08-19 10:02
Rank9

Iovance Biotherapeutics, Inc.

IOVA

+14.44%
US equitiesUnited States
Last 24 hourly closes · 1H
IOVA
Last price8.0450 USD
Change+14.44%
Intraday range12.03%
Volume vs baseline5.3×
Sigma move1.5 σ
Rank in past 100 days#5
Move started2026-08-19 13:30opening bell

Same thread as #1 MRNA — The first mRNA treatment meant to prevent cancer came back with positiv…

The catalyst, the mechanism, the posts and the sources all sit in that block. Nothing is repeated here.

Sources

Only the sources unique to this row. Anything already listed in that block is not repeated here.

Measured from
Leads
Secondary (media)MT Newswires2026-08-18 10:59Secondary (media)Stocktwits2026-08-19 01:54
Rank10

DRDGOLD Limited

DRD

+14.40%
US equitiesUnited States
Last 24 hourly closes · 1H
DRD
Last price27.80 USD
Change+14.40%
Intraday range3.42%
Volume vs baseline9.3×
Sigma move4.8 σ
Rank in past 100 days#1
Move started2026-08-19 13:30opening bell

Same thread as #8 HYMC — Hycroft +15%, DRDGOLD +14%, both gapping on the same opening bell

The catalyst, the mechanism, the posts and the sources all sit in that block. Nothing is repeated here.

Sources

Only the sources unique to this row. Anything already listed in that block is not repeated here.

Measured from
Leads
Secondary (media)MT Newswires2026-08-19 09:14First-partySEC EDGAR2026-08-19 14:27

Methodology

Evidence tier

Change
For crypto this is the exchange's rolling 24-hour figure (last price over the price 24 hours ago). For US equities it is the session change, previous close to last: US markets are shut about 17.5 hours a day, so a literal 24-hour window would fold two sessions into one number.
Volume vs baseline
Volume of the breakout bar divided by the median of the prior 20 bars. The baseline is a median, not a mean, so the spike cannot inflate its own denominator.
Sigma move
This move measured in standard deviations of the instrument's own 30-day realised volatility. The larger the number, the less it looks like ordinary noise.
Rank in past 100 days
Where this move ranks among the past 100 complete trading days. Rank 1 means the biggest in a hundred sessions.
Lag
Time between the catalyst event and the start of the move. If the event lands after the move began, the entry is marked unattributed.
Gap at the open
The news broke before the bell, so the repricing was finished by the time trading opened. This row's move starts at the opening bell itself, which means there is no lag to measure — and we do not print one.
Measured from
Price, volume and range for this row are measured here.
Leads
The events below pass the scope test but not the timing one — listed as leads, not as attributions.